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| Title: | | DNA-DRUG INTERACTIONS: THE CRYSTAL STRUCTURES OF D(TGTACA) COMPLEXED WITH DAUNOMYCIN | |
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| Molecular Description: | 5'-D(TpGpTpApCpA)-3'
DAUNOMYCIN |
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| Structural Features: | RH DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DT) (DG) (DT) (DA) (DC) (DA) |
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| Primary Citation: | Nunn, C.M., Van Meervelt, L., Zhang, S., Moore, M.H., Kennard, O.
DNA-Drug Interactions: The Crystal Structures of d(TGTACA) and d(TGATCA) Complexed with Daunomycin
J.Mol.Biol.
, 222,
pp. 167 - 177, 1991.
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| | | |
| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
|
|
| Cell Constants: |
| a = 28.020 | b = 28.020 | c = 52.710 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
25.0
for 1811 reflections
in the resolution range 10.000 to
1.600 Ångstroms
with Fobs > 3.000 sigma(Fobs).
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