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| Title: | | BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON | |
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| Molecular Description: | 5'-D((5CM)pGpTp(AS)p(5CM)pG)-3'
NOGALAMYCIN |
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| Structural Features: | RH DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (5CM) (DG) (DT) (AS) (5CM) (DG) |
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| Primary Citation: | Gao, Y.G., Liaw, Y.C., Robinson, H., Wang, A.H.
Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.
Biochemistry
, 29,
pp. 10307 - 10316, 1990.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
61
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| Cell Constants: |
| a = 26.310 | b = 26.310 | c = 100.250 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
20.8
for 3386 reflections
in the resolution of 1.700
with Fobs > 2.000 sigma(Fobs).
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