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| Title: |  | THE PRIMARY MODE OF BINDING OF CISPLATIN TO A B-DNA DODECAMER: C-G-C-G-A-A-T-T-C-G-C-G |  |
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| Molecular Description: | 5'-D(CpGpCpGpApApTpTpCpGpCpG)-3' CISPLATIN |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Wing, R.M., Pjura, P., Drew, H.R., Dickerson, R.E.
The primary mode of binding of cisplatin to a B-DNA dodecamer: C-G-C-G-A-A-T-T-C-G-C-G
EMBO J.
, 3,
pp. 1201 - 1206, 1984.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.160 | b = 39.930 | c = 66.120 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the JACK-LEVITT program.
The R value is
10.2
for 725 reflections
in the resolution range 8.000 to
2.600 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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