NDB ID: DR0007


Title:CRYSTAL STRUCTURE OF TOBRAMYCIN BOUND TO THE EUBACTERIAL 16S RRNA A SITE
Molecular Description:5'-R(UpUpGpCpGpUpCpApCpApCpCpGpGpUpGpAp
ApGpUpCpGpC)-3',TOBRAMYCIN
Structural Features:A DOUBLE HELIX, BULGES
Nucleic Acid Sequence:
ChainsA, B: U U G C G U C A C A C C G G U G A A G U C G C
Primary Citation:Vicens, Q., Westhof, E.
Crystal Structure of a Complex between the Aminoglycoside Tobramycin and an Oligonucleotide Containing the Ribosomal Decoding A Site
Chem.Biol. , 9, pp. 747 - 755, 2002.
Experimental Information:X-RAY DIFFRACTION
Space Group: 21   1
Cell Constants:
a = 46.900b = 32.800c = 52.000(Ångstroms)
= 90.00 = 107.90 = 90.00(degrees)
Crystallization Conditions:
Method:VAPOR DIFFUSION, HANGING DROP
Drop:MPD, sodium cacodylate, NaCl, KCl, MgSO4
Reservoir:MPD
Refinement:The structure was refined using the CNS 1.0 program. The R value is 21.4 for 4644 reflections in the resolution range 10 to 2.54 Ångstroms with Fobs > 1.5 sigma(Fobs).

Biological Unit 1
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Coordinate + Structure Data

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Unit coordinates (pdb format)

Structure Factors (cif format)

XML | Complete with coordinates (xml format, GNU compressed(.gz))
XML | Coordinates only (xml format, GNU compressed(.gz))
XML | Header only (xml format, GNU compressed(.gz))

Derivative Data

Nucleic Acid Backbone Torsions

Base Pair Parameters

Base Pair Step Parameters

Hydrogen Bonding Classification

Links

The Protein Data Bank: 1LC4

PubMed: 12079787




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