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| Title: | | 2.9 A CRYSTAL STRUCTURE OF STREPTOMYCIN RNA-APTAMER COMPLEX | |
|
| Molecular Description: | 5'-R(GpGpApUpCpGpCpApUpUpUpGpGpApCpUpUp
CpUpGpCpC)-3'
Streptomycin |
 |
| Structural Features: | DOUBLE HELIX, INTERNAL LOOP |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | A: | |
G G A U C G C A U U U G G A C U U C U G C C
|
| Chain | B: | |
C G G C A C C A C G G U C G G A U C
|
|
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| Primary Citation: | Tereshko, V., Skripkin, E., Patel, D.J.
Encapsulating Streptomycin within a small 40-mer RNA
CHEM.BIOL.
, 10,
pp. 175 - 187, 2003.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
I
4
|
|
| Cell Constants: |
| a = 82.634 | b = 82.634 | c = 49.153 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | MES buffer, MgCl2, NaCl, MPD |
| Reservoir: | | MgCl2, NaCl, MPD |
|
|
| Refinement: | The structure was refined using the REFMAC 5.1.13 program.
The R value is
20.373
for 3394 reflections
in the resolution range 20.00 to
2.90 Ångstroms
. |
|
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