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| Title: | | CRYSTAL STRUCTURE OF APRAMYCIN BOUND TO A RIBOSOMAL RNA A SITE OLIGONUCLEOTIDE | |
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| Molecular Description: | RNA/APRAMYCIN |
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| Structural Features: | A DOUBLE HELIX, BULGES, OVERHANGING BASES, FLIPPED-OUT BASES |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
U U G C G U C A C A C C G G U G A A G U C G C
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| Primary Citation: | Han, Q., Zhao, Q., Fish, S., Simonsen, K.B., Vourloumis, D., Froelich, J.M., Wall, D., Hermann, T.
Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex.
Angew.Chem.Int.Ed.Engl.
, 44,
pp. 2694 - 2700, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 92.250 | b = 30.900 | c = 45.810 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | EVAPORATION |
| Drop: | | MPD, sodium cacodylate, NaCl, KCl, MgSO4, H2O |
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| Refinement: | The structure was refined using the CNS program.
The R value is
24.6
for 3712 reflections
in the resolution range 8.0 to
2.7 Ångstroms
with I > 1.5 sigma(I).
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