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| Title: | | THE COMPLEX OF A NOVEL ANTIBIOTIC WITH THE AMINOACYL SITE OF THE BACTERIAL RIBOSOME REVEALED BY X-RAY CRYSTALLOGRAPHY. | |
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| Molecular Description: | 5'-R(CGpCpGpUpCpApCpApCpCpGpGpUpGpApApGp
UpCpGpC)-3'
PAROMOMYCIN (RING 2)
4-AMINO-2-HYDROXYBUTANOIC ACID |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
C G C G U C A C A C C G G U G A A G U C G C
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| Primary Citation: | Russell, R.J., Murray, J.B., Lentzen, G., Haddad, J., Mobashery, S.
The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography.
J.Am.Chem.Soc.
, 125,
pp. 3410 - 3411, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 32.800 | b = 46.550 | c = 88.810 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
25.07
for 5247 reflections
in the resolution range 30.0 to
2.4 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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