 | | | |
| Title: | | MOLECULAR RECOGNITION OF RNA BY NEOMYCIN AND A RESTRICTED NEOMYCIN DERIVATIVE | |
|
| Molecular Description: | 5'-R(GpUpGpGpUpGpApApGpUpCpGpCpGpG)-3' |
 |
| Structural Features: | A DOUBLE HELIX, BULGES, FLIPPED-OUT BASES, OVERHANGING BASES |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A, C: | |
G U G G U G A A G U C G C G G
|
| Chains | B, D: | |
C G C G U C A C A C C A C C
|
|
|
| Primary Citation: | Zhao, F., Zhao, Q., Blount, K.F., Han, Q., Tor, Y., Hermann, T.
Molecular recognition of RNA by neomycin and a restricted neomycin derivative
Angew.Chem.Int.Ed.Engl.
, 44,
pp. 5329 - 5334, 2005.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 50.740 | b = 50.750 | c = 144.720 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Crystallization Conditions: |
| Method: | | EVAPORATION |
| Drop: | | MPD, magnesium acetate, cacodylate, h2o |
| Reservoir: | | MPD, magnesium acetate, cacodylate, h2o |
|
|
| Refinement: | The structure was refined using the CNS program.
The R value is
23.3
for 5581 reflections
in the resolution range 8.0 to
3.0 Ångstroms
with I > 0 sigma(I).
|
|
|
