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| Title: |  | HIV-1 DIS KISSING-LOOP IN COMPLEX WITH RIBOSTAMYCIN |  |
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| Molecular Description: | 5'-R(CpUp(5BU)pGpCpUpGpApApGpUpGpCpApCp ApCpApGpCpApApG)-3' |
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| Structural Features: | SINGLE STRAND, hairpin loop |
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| Nucleic Acid Sequence: |
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| Chains | A,B,C,D: | | C U (5BU) G C U G A A G U G C A C A C A G C A A G |
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| Primary Citation: | Ennifar, E., Paillart, J.C., Bodlenner, A., Walter, P., Weibel, J.-M., Aubertin, A.-M., Pale, P., Dumas, P., Marquet, R.
Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.
Nucleic Acids Res.
, 34,
pp. 2328 - 2339, 2006.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 112.125 | b = 27.191 | c = 106.909 | (Ångstroms) |
= 90.00 | = 116.72 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
23.8
for 18763 reflections
in the resolution range 19.17 to
2.01 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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