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| Title: | | HIV-1 DIS KISSING-LOOP IN COMPLEX WITH LIVIDOMYCIN | |
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| Molecular Description: | 5'-R(CpUp(5BU)pGpCpUpGpApApGpUpGpCpApCp
ApCpApGpCpApApG)-3' |
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| Structural Features: | SINGLE STRAND, hairpin loop |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
C U (5BU) G C U G A A G U G C A C A C A G C A A G
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| Primary Citation: | Ennifar, E., Paillart, J.C., Bodlenner, A., Walter, P., Weibel, J.-M., Aubertin, A.-M., Pale, P., Dumas, P., Marquet, R.
Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.
Nucleic Acids Res.
, 34,
pp. 2328 - 2339, 2006.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
2
2
21
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| Cell Constants: |
| a = 27.137 | b = 115.335 | c = 95.254 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
24.5
for 26457 reflections
in the resolution range 9.94 to
1.80 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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