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| Title: | | ASITE RNA + DESIGNER ANTIBIOTIC | |
|
| Molecular Description: | 5'-R(GpCpGpUpCpApCpApCpCpGpGpUpGpApApGp
UpCpGpC)-3' |
 |
| Structural Features: | A DOUBLE HELIX, BULGES, FLIPPED-OUT BASES, OVERHANGING BASES |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | A: | | G C G U C A C A C C G G U G A A G U C G C |
| Chain | B: | | U U G C G U C A C A C C G G U G A A G U C G C |
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| Primary Citation: | Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
Chem.Biol.
, 13,
pp. 129 - 138, 2006.
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| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
1
21
1
|
|
| Cell Constants: |
| a = 45.976 | b = 32.926 | c = 46.414 | (Ångstroms) |
 = 90.00 |  = 95.62 |  = 90.00 | (degrees) |
|
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| Refinement: | The structure was refined using the CNS program.
The R value is
21.1
for 2735 reflections
in the resolution range 15.000 to
3.000 Ångstroms
with Fobs > 0.00 sigma(Fobs).
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