 | | | |
| Title: | | ASITE RNA + DESIGNER ANTIBIOTIC | |
|
| Molecular Description: | 5'-R(GpCpGpUpCpApCpApCpCpGpGpUpGpApApGp
UpCpGpC)-3' |
 |
| Structural Features: | A DOUBLE HELIX, BULGES, FLIPPED-OUT BASES |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A,B: | | G C G U C A C A C C G G U G A A G U C G C |
|
|
| Primary Citation: | Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
Chem.Biol.
, 13,
pp. 129 - 138, 2006.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 33.100 | b = 46.460 | c = 89.500 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS program.
The R value is
25.0
for 4290 reflections
in the resolution range 23.23 to
2.600 Ångstroms
with Fobs > 161.00 sigma(Fobs).
|
|
|
