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| Title: |  | CRYSTALLOGRAPHIC STUDIES OF DRUG-NUCLEIC ACID INTERACTIONS: PROFLAVINE INTERCALATION BETWEEN THE NON-COMPLEMENTARY BASE-PAIRS OF CYTIDILYL-3',5'-ADENOSINE |  |
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| Molecular Description: | 5'-R(CpAp)-3' PROFLAVINE |
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| Structural Features: | DOUBLE HELIX, PARALLEL HELIX |
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| Nucleic Acid Sequence: |
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| Primary Citation: | Westhof, E., Rao, S.T., Sundaralingam, M. Crystallographic Studies of Drug-Nucleic Acid Interactions: Proflavine Intercalation between the Non-Complementary Base-Pairs of Cytidilyl-3',5'-Adenosine
J.Mol.Biol.
, 142,
pp. 331 - 361, 1980.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
42
21
2
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| Cell Constants: |
| a = 19.380 | b = 19.380 | c = 27.100 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: |
The R value is
11.0
for 2454 reflections
in the resolution of 0.800
with I > 1.500 sigma(I).
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