NDB ID: DRB005


Title:CRYSTALLOGRAPHIC STUDIES OF DRUG-NUCLEIC ACID INTERACTIONS: PROFLAVINE INTERCALATION BETWEEN THE NON-COMPLEMENTARY BASE-PAIRS OF CYTIDILYL-3',5'-ADENOSINE
Molecular Description:5'-R(CpAp)-3'
PROFLAVINE
Structural Features:DOUBLE HELIX, PARALLEL HELIX
Nucleic Acid Sequence:
ChainA:C A
Primary Citation:Westhof, E., Rao, S.T., Sundaralingam, M.
Crystallographic Studies of Drug-Nucleic Acid Interactions: Proflavine Intercalation between the Non-Complementary Base-Pairs of Cytidilyl-3',5'-Adenosine
J.Mol.Biol. , 142, pp. 331 - 361, 1980.
Experimental Information:X-RAY DIFFRACTION
Space Group: 42   21   2
Cell Constants:
a = 19.380b = 19.380c = 27.100(Ångstroms)
= 90.00 = 90.00 = 90.00(degrees)
Refinement: The R value is 11.0 for 2454 reflections in the resolution of 0.800 with I > 1.500 sigma(I).

Biological Assembly 1
Other Views
Asymmetric Unit
Crystal Packing

Biological Assemblies



Coordinate + Structure Data

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format)

Derivative Data

Nucleic Acid Backbone Torsions

Base Pair Parameters

Base Pair Step Parameters

Hydrogen Bonding Classification




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