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| Title: |  | SIDE BY SIDE BINDING OF TWO DISTAMYCIN A DRUGS IN THE MINOR GROOVE OF AN ALTERNATING B-DNA DUPLEX |  |
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| Molecular Description: | 5'-D(IpCpIpCpIpCpIpC)-3' DISTAMYCIN |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DI) (DC) (DI) (DC) (DI) (DC) (DI) (DC) |
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| Primary Citation: | Chen, X., Ramakrishnan, B., Rao, S.T., Sundaralingam, M.
Binding of two distamycin A molecules in the minor groove of an alternating B-DNA duplex.
Nat.Struct.Biol.
, 1,
pp. 169 - 175, 1994.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
2
2
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| Cell Constants: |
| a = 27.930 | b = 27.930 | c = 57.670 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
15.0
for 2254 reflections
in the resolution range 10.000 to
1.800 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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