 | | | |
| Title: | | CRYSTAL STRUCTURE OF THE DNA DECAMER D(CGCAATTGCG) COMPLEXED WITH THE MINOR GROOVE BINDING DRUG NETROPSIN | |
|
| Molecular Description: | 5'-D(CpGpCpApApTpTpGpCpG)-3'
NETROPSIN |
 |
| Structural Features: | B DOUBLE HELIX, FLIPPED-OUT BASE, BASE TRIPLET, CONTINUOUS HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A,B: | | (DC) (DG) (DC) (DA) (DA) (DT) (DT) (DG) (DC) (DG) |
|
|
| Primary Citation: | Nunn, C.M., Garman, E., Neidle, S.
Crystal structure of the DNA decamer d(CGCAATTGCG) complexed with the minor groove binding drug netropsin.
Biochemistry
, 36,
pp. 4792 - 4799, 1997.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 24.840 | b = 39.800 | c = 54.080 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the X-PLOR program.
The R value is
20.1
for 1773 reflections
in the resolution range 8.000 to
2.400 Ångstroms
with Fobs > 2.000 sigma(Fobs).
|
|
|
