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| Title: |  | DEFINING GC-SPECIFICITY IN THE MINOR GROOVE: SIDE-BY-SIDE BINDING OF THE DI-IMIDAZOLE LEXITROPSIN TO C-A-T-G-G-C-C-A-T-G |  |
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| Molecular Description: | 5'-D(CpApTpGpGpCpCpApTpG)-3' DIIMIDAZOLE LEXITROPSIN |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DA) (DT) (DG) (DG) (DC) (DC) (DA) (DT) (DG) |
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| Primary Citation: | Kopka, M.L., Goodsell, D.S., Han, G.W., Chiu, T.K., Lown, J.W., Dickerson, R.E.
Defining GC-specificity in the minor groove: side-by-side binding of the di-imidazole lexitropsin to C-A-T-G-G-C-C-A-T-G.
Structure
, 5,
pp. 1033 - 1046, 1997.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 36.654 | b = 42.643 | c = 34.684 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
20.0
for 4895 reflections
in the resolution range 8.000 to
1.800 Ångstroms
with Fobs > 1.000 sigma(Fobs).
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