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| Title: | | A NOVEL END-TO-END BINDING OF TWO NETROPSINS TO THE DNA DECAMER D(CCCCCIIIII)2 | |
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| Molecular Description: | 5'-D(CpCpCp(CBR)pCpIpIpIpIpI)-3'
NETROPSIN |
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| Structural Features: | B DOUBLE HELIX, DOUBLE DRUG IN THE MINOR GROOVE |
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| Nucleic Acid Sequence: |
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| Chains | A,B,C,D: | | (DC) (DC) (DC) (CBR) (DC) (DI) (DI) (DI) (DI) (DI) |
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| Primary Citation: | Chen, X., Mitra, S.N., Rao, S.T., Sekar, K., Sundaralingam, M.
A novel end-to-end binding of two netropsins to the DNA decamers d(CCCCCIIIII)2, d(CCCBr5CCIIIII)2and d(CBr5CCCCIIIII)2.
Nucleic Acids Res.
, 26,
pp. 5464 - 5471, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
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| Cell Constants: |
| a = 32.660 | b = 32.770 | c = 37.710 | (Ångstroms) |
 = 86.01 |  = 84.37 |  = 68.90 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.1 program.
The R value is
19.0
for 3883 reflections
in the resolution range 8.000 to
2.400 Ångstroms
with Fobs > 4.000 sigma(Fobs).
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