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| Title: | | CRYSTAL STRUCTURE OF A PENTAMIDINE-OLIGONUCLEOTIDE COMPLEX: IMPLICATIONS FOR DNA-BINDING PROPERTIES | |
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| Molecular Description: | 5'-D(CpGpCpGpApApTpTpCpGpCpG)-3'
PENTAMIDINE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Edwards, K.J., Jenkins, T.C., Neidle, S.
Crystal structure of a pentamidine-oligonucleotide complex: implications for DNA-binding properties.
Biochemistry
, 31,
pp. 7104 - 7109, 1992.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.370 | b = 40.000 | c = 66.070 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
19.4
for 3113 reflections
in the resolution range 7.000 to
2.100 Ångstroms
with I > 2.000 sigma(I).
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