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| Title: | | CRYSTAL STRUCTURE OF A BERENIL-D(CGCAAATTTGCG) COMPLEX; AN EXAMPLE OF DRUG-DNA RECOGNITION BASED ON SEQUENCE-DEPENDENT STRUCTURAL FEATURES | |
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| Molecular Description: | 5'-D(CpGpCpApApApTpTpTpGpCpG)-3'
BERENIL |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DA) (DA) (DA) (DT) (DT) (DT) (DG) (DC) (DG) |
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| Primary Citation: | Brown, D.G., Sanderson, M.R., Garman, E., Neidle, S.
Crystal structure of a berenil-d(CGCAAATTTGCG) complex. An example of drug-DNA recognition based on sequence-dependent structural features.
J.Mol.Biol.
, 226,
pp. 481 - 490, 1992.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.640 | b = 40.610 | c = 65.070 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
18.3
for 3106 reflections
in the resolution range 7.000 to
2.000 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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