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| Title: | | BINDING OF AN ANTITUMOR DRUG TO DNA. NETROPSIN AND C-G-C-G-A-A-T-T-BRC-G-C-G | |
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| Molecular Description: | 5'-D(CpGpCpGpApApTpTp(CBR)pGpCpG)-3'
NETROPSIN |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (CBR) (DG) (DC) (DG) |
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| Primary Citation: | Kopka, M.L., Yoon, C., Goodsell, D., Pjura, P., Dickerson, R.E.
Binding of an antitumor drug to DNA, Netropsin and C-G-C-G-A-A-T-T-BrC-G-C-G.
J.Mol.Biol.
, 183,
pp. 553 - 563, 1985.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.270 | b = 39.620 | c = 63.570 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the JACK-LEVITT program.
The R value is
21.1
for 2528 reflections
in the resolution range 8.000 to
2.210 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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