 | | | |
| Title: | | MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG) COMPLEXED WITH HOECHST 33258 | |
|
| Molecular Description: | 5'-D(CpGpCp(G36)pApApTpTpCpGpCpG)-3'
HOECHST 33258 |
 |
| Structural Features: | B DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A,B: | | (DC) (DG) (DC) (G36) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
|
|
| Primary Citation: | Sriram, M., van der Marel, G.A., Roelen, H.L., van Boom, J.H., Wang, A.H.
Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.
EMBO J.
, 11,
pp. 225 - 232, 1992.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 25.640 | b = 41.310 | c = 66.990 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
14.5
for 1225 reflections
in the resolution of 2.500
with Fobs > 2.000 sigma(Fobs).
|
|
|
