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| Title: | | MINOR GROOVE BINDING OF SN6999 TO AN ALKYLATED DNA: MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG)-SN6999 COMPLEX | |
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| Molecular Description: | 5'-D(CpGpCp(G36)pApApTpTpCpGpCpG)-3'
SN6999 |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (G36) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Gao, Y.G., Sriram, M., Denny, W.A., Wang, A.H.
Minor groove binding of SN6999 to an alkylated DNA: molecular structure of d(CGC[e6G]AATTCGCG)-SN6999 complex.
Biochemistry
, 32,
pp. 9639 - 9648, 1993.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 28.480 | b = 36.110 | c = 69.600 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
17.0
for 1618 reflections
in the resolution range 10.000 to
2.250 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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