 | | | |
| Title: | | CRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX | |
|
| Molecular Description: |
HIGH MOBILITY GROUP PROTEIN HMG1/DNA COMPLEX |
 |
| Structural Features: | B DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Ohndorf, U.M., Rould, M.A., He, Q., Pabo, C.O., Lippard, S.J.
Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins.
Nature
, 399,
pp. 708 - 712, 1999.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
C
1
2
1
|
|
| Cell Constants: |
| a = 105.210 | b = 50.410 | c = 53.130 | (Ångstroms) |
 = 90.00 |  = 99.82 |  = 90.00 | (degrees) |
|
|
| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | MAGNESIUM ACETATE, HEPES, PEG
3350 GLYCEROL, DTT |
|
|
| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
23.8
for 17638 reflections
in the resolution range 100 to
2.5 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
