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| Title: | | LEUCINE-272-ALANINE URACIL-DNA GLYCOSYLASE BOUND TO ABASIC SITE-CONTAINING DNA | |
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| Molecular Description: | URACIL-DNA GLYCOSYLASE/DNA COMPLEX |
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| Structural Features: | RH DOUBLE HELIX, FLIPPED-OUT BASE, OVERHANGING BASE |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DT) (DG) (DT) (AAB) (DA) (DT) (DC) (DT) (DT) |
| Chain | B: | | (DA) (DA) (DA) (DG) (DA) (DT) (DA) (DA) (DC) (DA) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Parikh, S.S., Mol, C.D., Slupphaug, G., Bharati, S., Krokan, H.E., Tainer, J.A.
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.
EMBO J.
, 17,
pp. 5214 - 5226, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 120.300 | b = 48.800 | c = 65.600 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
18.4
for 17195 reflections
in the resolution range 20.0 to
2.25 Ångstroms
with Fobs > 2. sigma(Fobs).
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