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| Title: | | HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA | |
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| Molecular Description: |
MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE (E.C.4.2.99.18)/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX, FLIPPED-OUT BASES |
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| Nucleic Acid Sequence: |
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| Chains | X,U: | | (DG) (DC) (DT) (DA) (DC) (3DR) (DG) (DA) (DT) (DC) (DG) |
| Chains | Y,V: | | (DC) (DG) (DA) (DT) (DC) (DG) (DG) (DT) (DA) (DG) (DC) |
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| Protein Sequence: |
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| Primary Citation: | Mol, C.D., Izumi, T., Mitra, S., Tainer, J.A.
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Nature
, 403,
pp. 451 - 456, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
I
41
|
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| Cell Constants: |
| a = 122.85 | b = 122.85 | c = 107.07 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
19.0
for 11215 reflections
in the resolution range 20.0 to
2.95 Ångstroms
with Fobs > 3. sigma(Fobs).
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