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| Title: | | CRYSTAL STRUCTURE OF HUMAN APE1 BOUND TO ABASIC DNA | |
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| Molecular Description: |
MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE (E.C.4.2.99.18)/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Mol, C.D., Izumi, T., Mitra, S., Tainer, J.A.
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature
, 403,
pp. 451 - 456, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 71.221 | b = 72.249 | c = 93.749 | (Ångstroms) |
 = 90.00 |  = 94.292 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
19.5
for 22677 reflections
in the resolution range 20.0 to
2.65 Ångstroms
with Fobs > 4.0 sigma(Fobs).
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