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| Title: |  | CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING |  |
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| Molecular Description: | TRANSCRIPTION FACTOR CREB/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Chains | B,D: | | (DC) (DC) (DT) (DT) (DG) (DG) (DC) (DT) (DG) (DA) (DC) (DG) (DT) (DC) (DA) (DG) (DC) (DC) (DA) (DA) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Schumacher, M.A., Goodman, R.H., Brennan, R.G.
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding
J.Biol.Chem.
, 275,
pp. 35242 - 35247, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 110.610 | b = 49.320 | c = 79.250 | (Ångstroms) |
= 90.00 | = 122.18 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the TNT program.
The R value is
22.3
for 7316 reflections
in the resolution range 10. to
3.0 Ångstroms
with I > 1. sigma(I).
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