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| Title: | | CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN | |
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| Molecular Description: |
REVERSE TRANSCRIPTASE (E.C.2.7.7.49)/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Chains | E,F: | | (DT) (DT) (DT) (DC) (DA) (DT) (DG) (DC) (DA) (DT) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Najmudin, S., Cote, M.L., Sun, D., Yohannan, S., Montano, S.P., Gu, J., Georgiadis, M.M.
Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain
J.Mol.Biol.
, 296,
pp. 613 - 632, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 66.160 | b = 63.540 | c = 73.500 | (Ångstroms) |
 = 90.00 |  = 103.85 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
21.5
for 11540 reflections
in the resolution range 500. to
3.0 Ångstroms
with I > 0. sigma(I).
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