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| Title: | | CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA | |
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| Molecular Description: |
3-METHYL-ADENINE DNA GLYCOSYLASE (E.C.3.2.2.21)/DNA COMPLEX |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | D: | | (DG) (DA) (DC) (DA) (DT) (DG) (EDA) (DT) (DT) (DG) (DC) (DC) |
| Chain | E: | | (DG) (DC) (DA) (DA) (DT) (DC) (DA) (DT) (DG) (DT) (DC) (DA) |
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| Protein Sequence: |
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| Primary Citation: | Lau, A.Y., Wyatt, M.D., Glassner, B.J., Samson, L.D., Ellenberger, T.
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG.
Proc.Natl.Acad.Sci.USA
, 97,
pp. 13573 - 13578, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 42.145 | b = 57.336 | c = 125.517 | (Ångstroms) |
 = 90. |  = 90. |  = 90. | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
23.0
for 18163 reflections
in the resolution range 500. to
2.1 Ångstroms
with I > 1.0 sigma(I).
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