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| Title: | | CRYSTAL STRUCTURE OF A NF-KB HETERODIMER BOUND TO AN IFNB-KB | |
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| Molecular Description: |
Nuclear factor NF-kappa-B p65 subunit/Nuclear factor NF-kappa-B p50 subunit/DNA Complex |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASE |
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| Nucleic Acid Sequence: |
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| Chains | C,G: | | (DT) (DG) (DG) (DG) (DA) (DA) (DA) (DT) (DT) (DC) (DC) (DT) |
| Chains | D,H: | | (DA) (DA) (DG) (DG) (DA) (DA) (DT) (DT) (DT) (DC) (DC) (DC) |
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| Protein Sequence: |
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| Primary Citation: | Berkowitz, B., Huang, D.B., Chen-Park, F.E., Sigler, P.B., Ghosh, G.
The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site
J.Biol.Chem.
, 277,
pp. 24694 - 24700, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 137.525 | b = 138.015 | c = 89.320 | (Ångstroms) |
 = 90.00 |  = 97.25 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 0.9 program.
The R value is
26.0
for 37688 reflections
in the resolution range 20.0 to
2.75 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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