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| Title: | | CRYSTAL STRUCTURE OF THE CLOSED CONFORMATION OF BACILLUS DNA POLYMERASE I FRAGMENT BOUND TO DNA AND DCTP | |
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| Molecular Description: |
DNA POLYMERASE I (E.C.2.7.7.7)/DNA Complex |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | C,E: | | (DG) (DG) (DA) (DT) (DC) (DA) (DG) (DC) (DG) (DA) |
| Chains | D,F: | | (DA) (DC) (DG) (DT) (DC) (DG) (DC) (DT) (DG) (DA) (DT) (DC) (DC) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Johnson, S.J., Taylor, J.S., Beese, L.S.
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA
, 100,
pp. 3895 - 3900, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
31
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| Cell Constants: |
| a = 91.681 | b = 91.681 | c = 190.116 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
21.8
for 96536 reflections
in the resolution range 39.70 to
1.95 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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