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| Title: | | RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA) | |
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| Molecular Description: | Ribonuclease (E.C.3.1.27.5)/DNA Complex |
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| Structural Features: | SINGLE STRAND |
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| Nucleic Acid Sequence: |
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| Chains | C,D: | | (DA) (DC) (DG) (DA) |
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| Protein Sequence: |
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| Primary Citation: | Leu, Y.-J., Chern, S.-S., Wang, S.-C., Hsiao, Y.-Y., Amiraslanov, I., Liaw, Y.-C., Liao, Y.-D.
Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography
J.Biol.Chem.
, 278,
pp. 7300 - 7309, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 28.629 | b = 53.566 | c = 72.203 | (Ångstroms) |
 = 90.00 |  = 98.31 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
18.9
for 17518 reflections
in the resolution range 19.68 to
1.80 Ångstroms
with I > 0.0 sigma(I).
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