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| Title: | | ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE | |
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| Molecular Description: | Modification methylase HhaI/DNA Complex |
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| Structural Features: | B DOUBLE HELIX, FLIPPED OUT BASE |
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| Nucleic Acid Sequence: |
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| Chain | C: | | (DC) (DC) (DA) (DT) (DG) (DC) (DG) (DC) (DT) (DG) (DA) (DC) |
| Chain | D: | | (DG) (DT) (DC) (DA) (DG) Z (DG) (DC) (DA) (DT) (DG) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Zhou, L., Cheng, X., Connolly, B.A., Dickman, M.J., Hurd, P.J., Hornby, D.P.
ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
J.MOL.BIOL.
, 321,
pp. 591 - 599, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
H
3
2
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| Cell Constants: |
| a = 96.19 | b = 96.19 | c = 315.75 | (Ångstroms) |
 = 90.0 |  = 90.0 |  = 120.0 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
17.7
for 19591 reflections
in the resolution range 39.7 to
2.50 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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