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| Title: |  | HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA CONTAINING AN 8-OXO-7,8-DIHYDRO-GUANINE TEMPLATE PAIRED WITH DCTP |  |
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| Molecular Description: |
DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA Complex |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Krahn, J.M., Beard, W.A., Miller, H., Grollman, A.P., Wilson, S.H.
Structure of DNA Polymerase beta with the Mutagenic DNA Lesion 8-oxodeoxyguanine Reveals Structural Insights into its Coding Potential
Structure
, 11,
pp. 121 - 127, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 50.500 | b = 79.900 | c = 55.600 | (Ångstroms) |
= 90.00 | = 107.90 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
23.5
for 10177 reflections
in the resolution range 20.0 to
2.8 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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