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| Title: |  | HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO PRE-TRANSLOCATION AZTMP-TERMINATED DNA (COMPLEX N) |  |
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| Molecular Description: |
reverse transcriptase (E.C.2.7.7.49)/monoclonal antibody fab28 light and heavy chains/DNA |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Sarafianos, S.G., Clark Jr., A.D., Das, K., Tuske, S., Birktoft, J.J., Ilankumaran, I., Ramesha, A.R., Sayer, J.M., Jerina, D.M., Boyer, P.L., Hughes, S.H., Arnold, E.
Structures of HIV-1 Reverse Transcriptase with Pre- and Post-translocation AZTMP-terminated DNA
Embo J.
, 21,
pp. 6614 - 6624, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
32
1
2
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| Cell Constants: |
| a = 166.350 | b = 166.350 | c = 220.960 | (Ångstroms) |
= 90.00 | = 90.00 | = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
24.7
for 59280 reflections
in the resolution range 20. to
3. Ångstroms
with Fobs > 2. sigma(Fobs).
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