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| Title: |  | CYTOSINE-CYTOSINE MISMATCH AT THE POLYMERASE ACTIVE SITE |  |
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| Molecular Description: |
DNA polymerase I (E.C.2.7.7.7)/DNA Complex |
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| Structural Features: | B DOUBLE HELIX, overhanging base |
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| Nucleic Acid Sequence: |
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| Chain | B: | | (DG) (DC) (DA) (DT) (DG) (DA) (DT) (DC) (DC) |
| Chain | C: | | (DG) (DA) (DT) (DC) (DG) (DC) (DG) (DA) (DT) (DC) (DA) (DT) (DG) (DC) (DA) |
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| Protein Sequence: |
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| Primary Citation: | Johnson, S.J., Beese, L.S.
Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.)
, 116,
pp. 803 - 816, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 87.863 | b = 93.682 | c = 105.452 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
21.3
for 46660 reflections
in the resolution range 35.02 to
2.10 Ångstroms
with Fobs > 2.0 sigma(Fobs).
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