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| Title: | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COVALENTLY TETHERED TO DNA TEMPLATE-PRIMER SOLVED TO 2.8 ANGSTROMS | |
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| Molecular Description: |
Reverse transcriptase (E.C.2.7.7.49)/monoclonal antibody/DNA Complex |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Peletskaya, E.N., Kogon, A.A., Tuske, S., Arnold, E., Hughes, S.H.
Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA.
J.Virol.
, 78,
pp. 3387 - 3397, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
32
1
2
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| Cell Constants: |
| a = 165.820 | b = 165.820 | c = 220.720 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
23.9
for 76712 reflections
in the resolution range 19.96 to
2.80 Ångstroms
with Fobs > 1.1 sigma(Fobs).
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