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| Title: | | MUTY ADENINE GLYCOSYLASE IN COMPLEX WITH DNA CONTAINING AN A:OXOG PAIR | |
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| Molecular Description: | 5'-D(ApApGpApCp(8OG)pTpGpGpApC)-3'/5'-D(
TpGpTpCpCpApApGpTpCpT)-3'/MutY |
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| Structural Features: | B DOUBLE HELIX, INTERNAL LOOP, FLIPPED-OUT BASE, OVERHANGING BASE |
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| Nucleic Acid Sequence: |
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| Chain | B: | | (DA) (DA) (DG) (DA) (DC) (8OG) (DT) (DG) (DG) (DA) (DC) |
| Chain | C: | | (DT) (DG) (DT) (DC) (DC) (DA) (DA) (DG) (DT) (DC) (DT) |
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| Protein Sequence: |
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| Primary Citation: | Fromme, J.C., Banerjee, A., Huang, S.J., Verdine, G.L.
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature
, 427,
pp. 652 - 656, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
|
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| Cell Constants: |
| a = 37.763 | b = 85.699 | c = 142.088 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
22.6
for 21091 reflections
in the resolution range 36.69 to
2.22 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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