 | | | |
| Title: | | MUTY ADENINE GLYCOSYLASE IN COMPLEX WITH DNA CONTAINING AN ABASIC SITE | |
|
| Molecular Description: | 5'-D(ApApGpApCp(8OG)pTpGpGpApC)-3'/5'-D(
TpGpTpCpCpAp(HPD)pGpTpCpT)-3'/MutY |
 |
| Structural Features: | B DOUBLE HELIX, INTERNAL LOOP, OVERHANGING BASE |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | B: | | (DA) (DA) (DG) (DA) (DC) (8OG) (DT) (DG) (DG) (DA) (DC) |
| Chain | C: | | (DT) (DG) (DT) (DC) (DC) (DA) (HPD) (DG) (DT) (DC) (DT) |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Fromme, J.C., Banerjee, A., Huang, S.J., Verdine, G.L.
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature
, 427,
pp. 652 - 656, 2004.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 37.758 | b = 85.539 | c = 141.163 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
23.1
for 18059 reflections
in the resolution range 36.58 to
2.40 Ångstroms
with Fobs > .0 sigma(Fobs).
|
|
|
