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| Title: | | CRYSTAL STRUCTURE OF A. FULGIDUS FEN-1 BOUND TO DNA | |
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| Molecular Description: |
Flap structure-specific endonuclease/5'-d(
TpApGpCpApTpCpGpG) |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | C,D: | | (DT) (DA) (DG) (DC) (DA) (DT) (DC) (DG) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.)
, 116,
pp. 39 - 50, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
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| Cell Constants: |
| a = 86.843 | b = 86.843 | c = 250.519 | (Ångstroms) |
 = 90. |  = 90. |  = 90. | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
27.4
for 32212 reflections
in the resolution range 20. to
2.5 Ångstroms
with Fobs > 2. sigma(Fobs).
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