 | | | |
| Title: | | CRYSTAL STRUCTURE OF A. FULGIDUS FEN-1 BOUND TO DNA | |
|
| Molecular Description: | 5'-d(CpGpApTpGpCpTpA)-3'/5'-d(TpApGpCpA
pTpCpG
pG)-3'/Flap structure-specific endonuclease |
|
| Structural Features: | B DOUBLE HELIX, OVERHANGING BASE |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | B: | | (DC) (DG) (DA) (DT) (DG) (DC) (DT) (DA) |
| Chain | C: | | (DT) (DA) (DG) (DC) (DA) (DT) (DC) (DG) (DG) |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.)
, 116,
pp. 39 - 50, 2004.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
2
|
|
| Cell Constants: |
| a = 109.330 | b = 86.476 | c = 43.857 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
24.2
for 26938 reflections
in the resolution range 40. to
2.0 Ångstroms
with Fobs > 2.0 sigma(Fobs).
|
|
|
