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| Title: |  | CRYSTAL STRUCTURE OF AAV REP COMPLEXED WITH THE REP-BINDING SEQUENCE |  |
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| Molecular Description: | Rep PROTEIN/DNA Complex |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Hickman, A.B., Ronning, D.R., Perez, Z.N., Kotin, R.M., Dyda, F.
The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell
, 13,
pp. 403 - 414, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 78.671 | b = 131.706 | c = 82.164 | (Ångstroms) |
= 90.00 | = 112.68 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
28.6
for 23530 reflections
in the resolution range 19.88 to
3.10 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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