 |  |  |  |
| Title: |  | CRYSTAL STRUCTURE OF THE VIRAL ZALPHA DOMAIN BOUND TO LEFT-HANDED Z-DNA |  |
 |
| Molecular Description: | 34L PROTEIN/DNA Complex |
 |
| Structural Features: | Z DOUBLE HELIX |
 |
| Nucleic Acid Sequence: |
 |  |  |  |
| Chains | C, D: | |
(DT) (DC) (DG) (DC) (DG) (DC) (DG)
|
|
 |
| Protein Sequence: |
|
 |
| Primary Citation: | Ha, S.C., Lokanath, N.K., Van Quyen, D., Wu, C.A., Lowenhaupt, K., Rich, A., Kim, Y.G., Kim, K.K.
A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zalpha bound to DNA.
Proc.Natl.Acad.Sci.USA
, 101,
pp. 14367 - 14372, 2004.
|
 |
 |  |  |  |
| Experimental Information: | X-RAY DIFFRACTION |
 |
| Space Group: |
P
21
21
2
|
 |
| Cell Constants: |
| a = 51.203 | b = 92.452 | c = 48.012 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
|
 |
| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | lithium sulfate, magnesium chloride, cacodylate, H2O |
| Reservoir: | | lithium sulfate, magnesium chloride, H2O |
|
 |
| Refinement: | The structure was refined using the CNS program.
The R value is
23.75
for 15266 reflections
in the resolution range 20.0 to
2.0 Ångstroms
with Fobs > 0 sigma(Fobs).
|
|
|