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| Title: | | STRUCTURE OF THE CATALYTIC CORE OF DNA POLYMERASE IOTA IN COMPLEX WITH DNA AND DTTP | |
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| Molecular Description: |
polymerase (DNA directed) iota/DNA Complex |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Nair, D.T., Johnson, R.E., Prakash, S., Prakash, L., Aggarwal, A.K.
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing.
Nature
, 430,
pp. 377 - 380, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
65
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| Cell Constants: |
| a = 98.831 | b = 98.831 | c = 202.755 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
26.5
for 48071 reflections
in the resolution range 50. to
2.3 Ångstroms
with I > 0. sigma(I).
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