 | | | |
| Title: | | T7 DNA POLYMERASE TERNARY COMPLEX WITH 8 OXO GUANOSINE AND DCMP AT THE ELONGATION SITE | |
|
| Molecular Description: |
DNA POLYMERASE (E.C.2.7.7.7)/THIOREDOXIN 1/DNA Complex |
 |
| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES, FLIPPED-OUT BASE |
|
| Nucleic Acid Sequence: |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Brieba, L.G., Eichman, B.F., Kokoska, R.J., Doublie, S., Kunkel, T.A., Ellenberger, T.
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J.
, 23,
pp. 3452 - 3461, 2004.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
2
|
|
| Cell Constants: |
| a = 105.514 | b = 215.112 | c = 52.035 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
20.2
for 40853 reflections
in the resolution range 47.91 to
2.49 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
