 | | | |
| Title: | | AMINOFLUORENE DNA ADDUCT AT THE PRE-INSERTION SITE OF A DNA POLYMERASE | |
|
| Molecular Description: |
DNA polymerase I (E.C.2.7.7.7)/DNA Complex |
 |
| Structural Features: | B DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | B: | | (DA) (DG) (DG) (DG) (DA) (DT) (DG) (DG) (DT) (DG) |
| Chain | C: | | (DC) (DA) (DT) (DG) (DC) (DA) (DC) (DC) (DA) (DT) (DC) (DC) (DC) (DT) |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Hsu, G.W., Kiefer, J.R., Burnouf, D., Becherel, O.J., Fuchs, R.P.P., Beese, L.S.
Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase
J.Biol.Chem.
, 279,
pp. 50280 - 50285, 2004.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 87.868 | b = 93.471 | c = 104.656 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
21.0
for 47667 reflections
in the resolution range 37.17 to
2.10 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
