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| Title: | | STRUCTURE OF AMINOFLUORENE ADDUCT PAIRED OPPOSITE CYTOSINE AT THE POLYMERASE ACTIVE SITE. | |
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| Molecular Description: |
DNA polymerase I (E.C.2.7.7.7)/DNA Complex |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | B: | | (DA) (DG) (DG) (DG) (DA) (DT) (DG) (DG) (DT) (DG) (DC) |
| Chain | C: | | (DC) (DA) (DT) (DG) (DC) (DA) (DC) (DC) (DA) (DT) (DC) (DC) (DC) (DT) |
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| Protein Sequence: |
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| Primary Citation: | Hsu, G.W., Kiefer, J.R., Becherel, O.J., Fuchs, R.P.P., Beese, L.S.
Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase
J.Biol.Chem.
, 279,
pp. 50280 - 50285, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 87.639 | b = 93.441 | c = 105.465 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
21.6
for 56558 reflections
in the resolution range 33.70 to
2.00 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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