 | | | |
| Title: | | CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH A ONE NUCLEOTIDE DNA GAP AND DDTTP | |
|
| Molecular Description: | 5'-D(CpGpGpCpApApTpApCpTpG)-3'/ 5'-D(Cp
ApGpTpAp(2DT))-3'/ 5'-D(pGpCpCpG)-3' |
 |
| Structural Features: | B DOUBLE HELIX, NICKED |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | D: | | (DG) (DC) (DC) (DG) |
| Chain | P: | | (DC) (DA) (DG) (DT) (DA) (2DT) |
| Chain | T: | | (DC) (DG) (DG) (DC) (DA) (DA) (DT) (DA) (DC) (DT) (DG) |
|
|
| Protein Sequence: |
|
|
| Primary Citation: | Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Kunkel, T.A., Pedersen, L.C.
A closed conformation for the Pol lambda catalytic cycle.
Nat.Struct.Mol.Biol.
, 12,
pp. 97 - 98, 2005.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 56.043 | b = 62.551 | c = 139.830 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
21.3
for 33027 reflections
in the resolution range 35.84 to
1.95 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
