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| Title: | | CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH NICKED DNA AND PYROPHOSPHATE | |
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| Molecular Description: | 5'-D(CpGpGpCpCpGpTpApCpTpG)-3'/ 5'-D(Cp
ApGpTpApCpG)-3'/ 5'-D(pGpCpCp
G)-3'/ DNA polymerase lambda |
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| Structural Features: | B DOUBLE HELIX, NICKED |
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| Nucleic Acid Sequence: |
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| Chain | D: | | (DG) (DC) (DC) (DG) |
| Chain | P: | | (DC) (DA) (DG) (DT) (DA) (DC) (DG) |
| Chain | T: | | (DC) (DG) (DG) (DC) (DC) (DG) (DT) (DA) (DC) (DT) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Kunkel, T.A., Pedersen, L.C.
A closed conformation for the Pol lambda catalytic cycle.
Nat.Struct.Mol.Biol.
, 12,
pp. 97 - 98, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
|
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| Cell Constants: |
| a = 55.845 | b = 62.758 | c = 140.720 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
20.6
for 24337 reflections
in the resolution range 41.72 to
2.20 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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