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| Title: | | X-RAY DATA DO NOT SUPPORT HOOGSTEEN BASE-PAIRING DURING REPLICATION BY HUMAN POLYMERASE IOTA | |
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| Molecular Description: |
POLYMERASE (DNA DIRECTED) IOTA/DNA Complex |
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| Structural Features: | B DOUBLE HELIX, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Protein Sequence: |
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| Primary Citation: | Wang, J.
DNA polymerases: Hoogsteen base-pairing in DNA replication?
Nature
, 437,
pp. E6 - 7; discussion E7, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
65
2
2
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| Cell Constants: |
| a = 98.831 | b = 98.831 | c = 202.755 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
26.1
for 26413 reflections
in the resolution range 39.43 to
2.30 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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